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Palbociclib (PD0332991) Isethionate

CAS No. 827022-33-3

Palbociclib (PD0332991) Isethionate ( —— )

Catalog No. M16070 CAS No. 827022-33-3

Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 42 In Stock
10MG 60 In Stock
50MG 78 In Stock
100MG 114 In Stock
200MG 141 In Stock
500MG 294 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Palbociclib (PD0332991) Isethionate
  • Note
    Research use only, not for human use.
  • Brief Description
    Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM.
  • Description
    Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK2/CyclinA; CDK2/CyclinE2; CDK4/CyclinD1; CDK4/CyclinD3; CDK6/CyclinD2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    827022-33-3
  • Formula Weight
    573.66
  • Molecular Formula
    C24H29N7O2·C2H6O4S
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 50 mg/mL warmed (87.15 mM)
  • SMILES
    OCCS(O)(=O)=O.CC(=O)C1=C(C)C2=CN=C(NC3=NC=C(C=C3)N3CCNCC3)N=C2N(C2CCCC2)C1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fry DW, et al. Mol Y Ther, 2004, 3(11), 1427-1438.
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